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Unfortunately, like other GLP1R agonists, retatrutide also produced significant GI side effects in a large proportion of participants (35% in the 36 week study and 45% in the 48 week study at the 12 mg dose) (Rosenstock et al., 2023)
(US), Amgen Inc
In particular, we observed that the -1 subcluster expressed low levels of ARX , IRX2 , CRYBA2 , ALDH1A1 , and TM4SF4
We know, because we test it
Common side effects include: Nausea Vomiting Diarrhea Constipation Bloating Stomach discomfort Indigestion These side effects are typically most noticeable when treatment begins or when doses are increased
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